This page contains PanRank candidate gene rankings based on gene panels from Genes4Epilepsy, a curated list of monogenic epilepsy genes. PanRank scores are between 0 and 1 and represent the predicted probability that a gene is disease-causing with the specified mode of inheritance. The “Known Inheritance” column indicates the known mode of inheritance used to train the model.

Choose the Epilepsy phenotype and gene subset below. By default, genes are sorted by decreasing PanRank Dominant score, and only genes not yet associated with the selected phenotype (“novel” genes) are shown. Hover over gene names for a description as well as links to external resources.

Note: “GGE” and “Focal” phenotypes have insufficient numbers of recessively inherited genes for training so no predictions are made.

PanRank is developed by Jacob E. Munro, Mark F. Bennett and Melanie Bahlo